Questions posted in the The Urology Forum have been answered by urologists from Henry Ford Health System and by Dr. Kevin Pho.

Question Title: Interstitial Cystitis & Ovulation

Forum: The Urology Forum
Topic: Cystisis

My wife's IC symptoms went into remission during a recent
pregnancy and while breastfeeding. Upon weaning, her menstrual
cyles started and IC symptoms returned and became very severe
during ovulation. Question is - has any link ever been studied
or established between IC and hormone levels, i.e., estrogen or
progesterone?
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Dear Jim Thanks for your questions?

As you know IC is a very complex disease. We the medical community still have a lot to learn about IC . Yes, cases of IC have been reported to go into remission, but not the majority of cases. The fact that this disease is about 10x more frequent in women suggests that this disease may have an association with the female hormonal milieu. Some treatments in other countries involve medications that shut down the sex hormone production in female IC patients. This drug is used in this country to treat prostate cancer which is known to be responsive to sex hormone levels.
We have almost as much contradictory information regarding IC hormonal association also.
We can only treat patients as best as we can until we learn more about the pathophysiology and hence of the disease.
Another possible diagnosis is endometriosis. This disease has pelvic pain similar to IC , however it is most intense during menstruation.

More individualized care is available at the Henry Ford Hospital and its urban campuses by calling (1 800 653 6568). We can also arrange local accommodations through this number if this is your need. Please bring any physicians’ notes and lab test results that you may be able to obtain. These will help us greatly.

This information is provided for general medical education purposes only. Please consult your physician for diagnostic and treatment options pertaining to your specific medical condition.
Sincerely;
HFHS-M.D. MS
* Keyword: Interstitial cystitis, endometreosis





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